CTIS retrieves organisation data from Organisation Management Service (OMS). The organisations that need to be registered in OMS in order to be available for CTIS are sponsors, co-sponsors, third party contractor (e.g. CRO), and marketing authoristation holders. Clinical trial sites are often already registered in OMS, but if not, they can be entered directly in CTIS without requiring registration in OMS.
If an organisation is not yet registered in OMS when starting to use CTIS, it is necessary to register the organisation via a request in OMS. Access to OMS is on the EMA SPOR portal (SPOR means: Substance, Product, Organisation, Referentials management services). The registration process of a new organisation in OMS can take up to 10 working days.
More information is provided in section 1.2 of the CTIS Sponsor Handbook of EMA.